In this episode, we sit down with Shane Gleason, Chief Commercial Officer at InspireMD, to talk about what it means to bring a new carotid stent to market at a time when treatment options are evolving. Shane shares how his two decades in the vascular space shaped the way he evaluates timing, team, and technology, and why those factors mattered when he decided to join InspireMD. He also walks through the details of their flexible open-celled nitinol stent with a finely woven PET mesh, explaining what it does, how it behaves, and why physicians have responded so strongly to it. The conversation moves from device design to clinical trials, commercial planning, and the changing landscape following CMS’s expanded coverage for carotid stenting. 🎧 This episode goes inside the work behind developing and launching a new carotid stent, and how the right timing, the right team, and a device designed for lasting protection can shift practice. 04:50 Why carotid procedures still make him sweat after hundreds of cases 06:14 What lasting protection means and why post-procedure events matter 07:01 Dual antiplatelet therapy and how the PET mesh behaves in the vessel 07:33 Showing the stent on camera and explaining the woven PET mesh 08:36 TCAR, transfemoral approaches, and what current trials are studying 11:12 How Shane’s team is approaching commercialization in the U.S. 12:22 Why the procedure attracts experienced reps and how they support cases 14:17 Why physicians say they’ve “been waiting for this for 20 years” 16:02 What it means to be the only company singularly focused on carotid disease 💡 Who Should Listen This episode is for vascular surgeons, neurointerventionalists, industry professionals supporting carotid interventions, and anyone following the current shift in carotid disease treatment and device innovation. About Shane Mr. Gleason has over 20 years of experience in the medical device industry leading clinical and commercial operations in both public and privately held companies. Prior to joining InspireMD, he served as Vice President of Sales, Vascular Interventions at Surmodics, a medical device company focused on addressing unmet clinical needs in intravascular medicine. Prior to Surmodics, Mr. Gleason served in a variety of leadership roles in the interventional medical device space, to include Senior Director, US Transcatheter Heart Valves Marketing for Edwards Lifesciences, a developer of artificial heart valve technologies; Chief Commercial Officer of Nuvaira, a privately held developer of therapies that preserve patient lung health; and Vice President of Sales roles with both Cordis, a Cardinal Health company, and TriVascular Technologies, now part of Endologix. He began his medical device career with a variety of progressive leadership roles at Abbott Vascular, where he launched the second FDA approved carotid stent system. Mr. Gleason received his B.S. in Engineering Science and Mechanics from Virginia Polytechnic Institute and State University and his M.B.A. from the University of Maryland’s Smith School of Business. Connect with Shane 💼 LinkedIn: Shane Gleason 🌐 InspireMD: inspiremd.com/team/shane-gleason/ About InspireMD InspireMD is a global carotid-focused company dedicated to helping prevent stroke, save lives, and give physicians and patients the confidence to choose carotid stenting without compromise. Based in Miami, the company is leading an international effort to advance carotid artery intervention through thoughtful engineering and a commitment to innovation. Their mission centers on one idea: stroke prevention is the blueprint, not an afterthought. With a focus on smarter design and strong clinical data, InspireMD aims to protect against carotid plaque prolapse and support physicians with a solution built for safety and clarity. CGuard® Prime, the company’s flagship product, is a next-generation carotid stent featuring a dual-layer design with a finely woven MicroNet™ mesh. It is the only FDA-approved mesh-covered carotid stent and was designed to offer a new layer of defense against the risk of plaque prolapse and embolization. In pivotal studies, CGuard Prime demonstrated the lowest independently adjudicated 30-day and 1-year major adverse event rates reported to date. Learn more about InspireMD 🌐 Website: inspiremd.com/ Follow Life of Flow 📲 Instagram: @LifeofFlowPodcast 👍 Facebook: Life of Flow Podcast 💼 LinkedIn: Life of Flow Podcast 🐦 X: @VascularPodcast If this episode gave you a new perspective on carotid disease treatment, device innovation, or the future of carotid stenting, share it with a colleague who would value the conversation. And if you’ve been enjoying Life of Flow, leaving a short review helps more listeners find stories like this one.

En este episodio de Life of Flow Podcast, conversamos con el Dr. Dimitrios Miserlis, M.D., profesor asistente de cirugía vascular en UT Dell y cirujano vascular en Ascension Seton, Austin. El Dr. Miserlis comparte su mirada sobre cómo la inteligencia artificial está transformando la práctica médica, desde los diagnósticos por imagen hasta la robótica quirúrgica. A lo largo de la charla, reflexiona junto a Lucas Ferrer y Miguel Montero-Baker sobre el equilibrio entre ciencia, filosofía y propósito humano en la evolución tecnológica. ❗️Este episodio, grabado originalmente en inglés y ahora doblado al español, captura una conversación honesta sobre liderazgo médico, trabajo interdisciplinario y el futuro de la atención basada en valor. English Version of the Episode 👉youtube.com/watch?v=FiJY_AtEEYg 02:00 Orígenes en Grecia y el camino hacia la medicina en EE. UU. 05:00 Primeros pasos en investigación y llegada a Texas 07:00 Cómo el entorno y las personas impulsan la innovación 10:00 De qué hablamos realmente cuando hablamos de inteligencia artificial 12:00 El test de Turing y los pilares de la IA moderna 15:00 Aplicaciones médicas: de la radiología a los sistemas diagnósticos 18:00 Los límites de la IA: imaginación, intuición y creatividad 22:00 Robótica blanda y medicina inclusiva 26:00 Riesgos, control y el desafío de comprender los algoritmos 31:00 Comunicación entre científicos y propósito en la innovación médica 💡¿Quién debería escuchar este episodio? Profesionales de la salud, investigadores y emprendedores del ámbito médico-tecnológico interesados en entender cómo la inteligencia artificial y la robótica están redefiniendo la práctica clínica y los desafíos éticos que esto plantea. Sobre Dr. Miserlis, MD Dimitrios Miserlis, MD, es un cirujano vascular con certificación de especialidad en Ascension Seton (Austin y Bastrop, Texas). Está especializado en flebología y en la evaluación y el tratamiento integral de las enfermedades venosas. Como experto en el sistema vascular, está altamente capacitado para tratar todo tipo de patologías de los vasos sanguíneos. Cada consulta con el Dr. Miserlis comienza con una conversación: dedica el tiempo necesario para responder todas las preguntas, grandes o pequeñas. 🌐 Ascension: healthcare.ascension.org/find-care/provider/1720375348/dimitrios-miserlis Sigue a Life of Flow 📲 Instagram: @LifeofFlowPodcast 👍 Facebook: Life of Flow Podcast 💼 LinkedIn: Life of Flow Podcast 🐦 X: @VascularPodcast ¿Conoces a alguien que debería escuchar esta conversación? 🎧 Envíale este episodio y ayúdanos a que más personas accedan a estas historias y aprendizajes.

In this episode of the Life of Flow Podcast, we talk with Mathias Ihlenfeld, an Austin-based entrepreneur, coach, and founder of Woom Bikes USA. Mathias shares how he went from landing in the U.S. with a tennis racket and a dream to building one of the country’s leading children’s bike brands. He reflects on what it takes to start over, listen to change when it calls, and channel energy into building something that lasts. 🎧 This episode dives into the work behind reinvention. How clarity, conviction, and persistence can turn a single idea into a purpose-driven business that grows with heart. 02:00 From Frankfurt to Louisiana: finding home in a new country 04:55 How moving between U.S. states felt like crossing countries 08:30 The power of reinvention and why resilience matters 11:20 From corporate consulting to founding Woom 14:35 The subtle (and not-so-subtle) signs it’s time to change course 16:50 The “hero’s journey” and how it shows up in real life 22:05 From selling 13 bikes to leading a multimillion-dollar company 23:40 Creating a brand that connects with families everywhere 25:10 Energy, focus, and passion: what drives sustainable growth 28:38 Balancing two careers, family, and the long view of success 💡 Who Should Listen For founders, builders, and anyone standing at a crossroads. This episode speaks to those who want to grow with purpose and are ready to rebuild their next chapter with intention. About Mathias Mathias Ihlenfeld is an award-winning entrepreneur, the Austin, TX Cohort Leader and Coach for the Birthing of Giants Regional Cohort, a selective fellowship program for growth-focused founders and CEOs building high-impact companies. He is also the creator of The R.E.C.L.A.I.M. Code (Elite Personal Optimization Framework for divorced high performers). His proprietary 6-stage framework helps divorced founders rebuild identity, attract aligned love, and ignite purpose-driven business performance. As the founder of Woom Bikes USA, Mathias built one of North America’s fastest-growing direct-to-consumer kids’ bike companies, earning multiple Inc. 5000 honors, including a 742% three-year growth rate in 2020, and recognition as one of the fastest-growing private companies in the U.S. In 2021, he played a pivotal role in merging the U.S. and European operations, leading the combined $100M global business as CEO in 2022 and 2023. His leadership has been recognized with honors such as Ernst & Young Entrepreneur of the Year finalist and the Vistage Impact Leadership Award. Through his coaching practice, he works with founders, executives, and high-achieving men navigating personal reinvention, guiding them through identity rebuilding, emotional mastery, business growth, and relationship alignment. Today, Mathias mentors with SKU, invests in purpose-driven brands, and writes on his Substack, sharing hard-earned lessons, strategic insight, and stories from his journey building global brands and leading life transformations. Connect with Mathias 📲 Instagram: @sundaygog 💼 LinkedIn: Mathias Ihlenfeld 🌐 MentorPass: mentorpass.co/mathiasihlenfeld Follow Life of Flow 📲 Instagram: @LifeofFlowPodcast 👍 Facebook: Life of Flow Podcast 💼 LinkedIn: Life of Flow Podcast 🐦 X: @VascularPodcast If this episode shifted your view on entrepreneurship, leadership, or starting over, share it with someone who would value the conversation. And if you’ve been enjoying Life of Flow, leaving a short review helps more listeners find stories like this one.