A conversation that starts with one set of “normal” labs and quickly turns into a deeper question: what does “healthy” mean? In this week’s episode, Lauren Colletti walks through how she evaluates patients beyond standard ranges, why so few people are truly metabolically healthy, and how tools like peptides, continuous glucose monitoring, and advanced labs are being used in practice today.
The episode moves between clinical reasoning and real-world experimentation, including what changed when Lucas became the patient.
04:30 Why “normal” labs may not mean optimal health
04:54 Only 12% of people are metabolically healthy
06:44 What peptides are and how they work
10:32 Curiosity, self-experimentation, and patient empowerment
17:08 Case breakdown: labs, symptoms, and treatment plan
23:12 Immediate changes in sleep, recovery, and performance
28:35 What technology can’t replace: human connection in care
33:15 Is ChatGPT your new doctor?
46:00 Innovation, risk, and pushing beyond traditional models
55:00 Lauren’s clinic and Soul Women initiative
Who Should Listen
Physicians, clinicians, and healthcare professionals who are thinking about prevention, metabolic health, or integrating newer tools into patient care.
About Lauren Colletti
Lauren Colletti is a board-certified Nurse Practitioner in functional medicine and anti-aging medicine. She has been working in the space for about 15 years, focusing on identifying root causes of health issues and integrating advanced testing and therapies into patient care. She is the co-founder of Alive and Well, a clinic with multiple locations, and the founder of Sol Women, a program focused on helping women navigate midlife through functional medicine, coaching, and community.
Connect with Lauren
💼 LinkedIn: Lauren Colletti
📲 Instagram: @laurencolletti_fnp
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If this episode changed how you think about prevention, metabolic health, and what it means to optimize your own physiology as a clinician, share it with a colleague who’s navigating the same questions. And if you’re enjoying Life of Flow, a quick review helps other physicians find conversations like this.
